Medications for Hair Growth
Bimatoprost (Latisse) & Latanoprost
Available by prescription only.
- Prostaglandin Analogue: Prostaglandins are naturally occurring substances in the body that play various roles, including regulating hair growth cycles.
- Prolonged Anagen Phase: One of the mechanisms proposed for the effect on hair growth is its ability to prolong the anagen (growth) phase of the hair follicle cycle. This means that more hairs remain in the active growth phase for a longer period, leading to longer and thicker hair growth.
- Increased Hair Pigmentation: Bimatoprost has also been shown to increase the pigmentation (color) of hair. This effect can be beneficial for individuals experiencing hair thinning or loss associated with conditions like alopecia areata or androgenetic alopecia.
- Off-Label Use: Due to its potential to stimulate hair growth, latanoprost is sometimes used off-label for treating conditions like alopecia areata, eyebrow hypotrichosis, and even male or female pattern hair loss (androgenetic alopecia). However, the evidence supporting its use in these conditions varies, and more research is needed to establish its efficacy and safety in these contexts.
- Application: When used for hair growth, latanoprost is typically applied topically to the affected area (e.g., scalp, eyebrows) in the form of a solution or gel. The frequency and duration of use may vary depending on the specific condition being treated and should be guided by a healthcare provider.
Finasteride & Dutasteride
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Minoxidil
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Mechanism of Action: Minoxidil is a vasodilator, meaning it widens blood vessels. Its exact mechanism in promoting hair growth is not fully understood, but it is believed to work by 1) i
ncreasing blood flow to the hair follicles, which can deliver more nutrients and oxygen to promote hair growth, and 2) prolonging the growth phase (anagen phase) of the hair follicles, leading to thicker and longer hair. - Application: Minoxidil is typically applied directly to the scalp in the form of a solution or foam. It is available over-the-counter in various strengths (2% for women, 5% for men) and as prescription-strength formulations.
- Effectiveness: Minoxidil is effective in promoting hair growth in about 30-40% of people who use it. It is most effective in individuals with recent hair loss and in areas where the hair is thinning but not completely gone. Results vary from person to person, and visible results may take several months of consistent use.
- Maintenance: To maintain hair growth, minoxidil needs to be used continuously. If treatment is stopped, any new hair growth will typically be lost within a few months to a year, and the scalp will return to its pre-treatment state.
- Side Effects: Common side effects of minoxidil include scalp irritation, itching, dryness, and redness. In some cases, it can cause unwanted hair growth on other parts of the body if it comes into contact with areas other than the scalp. Rare but more serious side effects may include dizziness, chest pain, or rapid heartbeat, which should be reported to a healthcare provider immediately.
- Combination Therapy: Minoxidil is often used in combination with other treatments for hair loss, such as finasteride (a medication that blocks the hormone DHT, which is implicated in hair loss) or hair transplant surgery, to achieve more significant and longer-lasting results.